Spielplan
| Termin | Tipptermin | Heim | Gast | Ergebnis | Punkteregel |
|---|---|---|---|---|---|
| 08.01.22 22:30 | 08.01.22 22:30 | Denver Broncos | Kansas City Chiefs | 24:28 | 7 - 7 - 4 |
| 09.01.22 02:15 | 09.01.22 02:15 | Philadelphia Eagles | Dallas Cowboys | 26:51 | 6 - 7 - 4 |
| 09.01.22 19:00 | 09.01.22 19:00 | New York Giants | Washington Football Team | 7:22 | 7 - 7 - 4 |
| 09.01.22 19:00 | 09.01.22 19:00 | Jacksonville Jaguars | Indianapolis Colts | 26:11 | 7 - 7 - 4 |
| 09.01.22 19:00 | 09.01.22 19:00 | Detroit Lions | Green Bay Packers | 37:30 | 7 - 7 - 4 |
| 09.01.22 19:00 | 09.01.22 19:00 | Cleveland Browns | Cincinnati Bengals | 21:16 | 6 - 7 - 4 |
| 09.01.22 19:00 | 09.01.22 19:00 | Baltimore Ravens | Pittsburgh Steelers | 13:16OT | 5 - 7 - 5 |
| 09.01.22 19:00 | 09.01.22 19:00 | Houston Texans | Tennessee Titans | 25:28 | 7 - 7 - 4 |
| 09.01.22 19:00 | 09.01.22 19:00 | Minnesota Vikings | Chicago Bears | 31:17 | 4 - 7 - 7 |
| 09.01.22 22:25 | 09.01.22 22:25 | Arizona Cardinals | Seattle Seahawks | 30:38 | 4 - 7 - 7 |
| 09.01.22 22:25 | 09.01.22 22:25 | Los Angeles Rams | San Francisco 49ers | 24:27OT | 4 - 7 - 6 |
| 09.01.22 22:25 | 09.01.22 22:25 | Buffalo Bills | New York Jets | 27:10 | 4 - 7 - 7 |
| 09.01.22 22:25 | 09.01.22 22:25 | Atlanta Falcons | New Orleans Saints | 20:30 | 6 - 7 - 4 |
| 09.01.22 22:25 | 09.01.22 22:25 | Miami Dolphins | New England Patriots | 33:24 | 7 - 7 - 4 |
| 09.01.22 22:25 | 09.01.22 22:25 | Tampa Bay Buccaneers | Carolina Panthers | 41:17 | 4 - 7 - 7 |
| 10.01.22 02:20 | 10.01.22 02:20 | Las Vegas Raiders | Los Angeles Chargers | 35:32OT | 5 - 7 - 4 |